Endocrine Abstracts

A 38 female patient with a diagnosis of primary CNS lymphoma was admitted for MATRIX (methotrexate, rituximab, thiopeta, cytarabine) chemotherapy. Prior to chemotherapy and while on steroids she became increasingly polydipsic and polyuric with blood biochemistry demonstrating a sodium of 164 mmol/l. An endocrine review of the patient was requested and a diagnosis of cranial diabetes insipidus was suspected due to the extent of infiltration of the hypothalamus and pituitary sta...

A 36-year-old female was referred to Endocrinology by her GP in August 2019 with polycythaemia, obesity, hypertension, type 2 diabetes, asthma, right shoulder and bilateral ankle pain [on 6-monthly steroid injections], easy bruising, hirsutism, PCOS and raised testosterone. Haematology had excluded likely causes of polycythaemia [JAK 2 negative]. The GP noted previous review by Endocrinology in another hospital [December 2012] regarding possible PCOS but was lost to follow up ...

We describe a 68 year lady who was found to have bilateral adrenal masses (7 cm on the right side and 1.3 cm on the left) during investigations for gastrointestinal symptoms, in early 2016. Biochemistry revealed high urinary normetanephrines of 41.7pmol/24h (ref 0–3) and metanephrines of 40pmol/24h (ref 0–1.8). A PET and MIBG scan revealed uptake in both adrenals and therefore a diagnosis of bilateral phaeochromocytoma was made. The patient had complained of occasion...